According Hindra, the doctors now do not prescribe aspirin (salicylates) to reduce fever in kids. Agency for the United States Food and Drug Administration (FDA) a while ago recommended that aspirin, as well as various products that contain aspirin (acetylsalicylic, asetilsalisilik, salicylic acid), not given to kids more youthful than 19 years.
Aspirin is called a pain reliever (analgesic), anti-inflammatory (anti-inflammatories), and lowering fever (antipyretic) is not recommended for kids. Drugs that cause Reye's syndrome. It was said to be a pediatrician from RSCM, Dr. Irawan Satari Hindra SpA, and from Hospital Sources Sane, Dr. Tatang Kustimansamsi SpA, to update on Wednesday (28 / 8).
Aspirin, Tatang said, could destroy the liver function (liver), causing Reye's syndrome. To relieve pain and reduce fever in kids, is currently recommended paracetamol (acetaminophen) because of side effects is low and affordable.
"A long time, aspirin is widely used and regarded as a drug powerful , but then the reported incidence of Reye's syndrome due to aspirin. Paracetamol is currently a first choice, but the dose ought to even be thought about," said Hindra.
Tatang said, Reye's syndrome not only occur in kids but also adults. Syndrome is caused by aspirin and various viruses, such as influenza virus, the chickenpox virus, or viruses that cause diarrhea. The organs of the body that plenty of viruses assault the liver and brain are the signs of high fever, convulsions, unconsciousness, and diarrhea.
Reye's syndrome
If somebody has a fever, seizures, or diarrhea alternately a day to days, you ought to consult a health care middle to ascertain whether Reye's syndrome or ordinary fever. It can be known through examination of blood and liver biopsy.
Blood tests and liver function in general is not difficult in Indonesia. However, examination of levels of ammonia (NH3) is difficult because of limited equipment. High ammonia levels in the blood makes a person a seizure. While liver biopsy to make sure Reye's syndrome was completed in collaboration with the Singapore.
Paracetamol
"Every year, there's cases of Reye's syndrome, although incidence is not high. Reye's syndrome, if untreated, can be cured. But there's survivors, but because the brain is broken, then arises of disability, such as poor speech. To note, not every smallpox or influenza cause Reye's syndrome, "he said.
Aspirin thins the blood is so that individuals who experience gastrointestinal issues (ulcers) is not advisable to drink, unless in the form mikrogranulasi. Aspirin is wrapped so as not to rupture in the stomach and absorbed in the intestine. According Sinaga, because it thins the blood, aspirin is widely used as a cure for coronary heart disease and rheumatic diseases.
Meanwhile, a biochemist from the National University, Dr Apt Ernawati Sinaga, said some drugs to kids still contain salicylates.
For kids, the dose of paracetamol ranges from 10-15 milligrams / kilogram of body weight. Drinking well over0 times the recommended dose can poison (destroy) the liver. Paracetamol can be administered orally, rectal (anal), and pre-drug parenteral (through blood vessels) are often used postoperatively.
Likewise with paracetamol, used to treat rheumatism. Use of aspirin as a cure rheumatism, Tatang said, need to be monitored. While paracetamol is not recommended for individuals who have weakened liver function. In addition to aspirin and paracetamol, ibuprofen (nonsteroidal anti-inflammatory drugs are) also used in kids to reduce fever and pain reliever.
If administered orally (tablets and liquids), the drug was quickly absorbed in the small intestine with a bioavailability ranging from 85 to 98 percent. With half time to hours, the buildup does not occur at the recommended dosage.
Therefore the use of aspirin is not recommended for kids.
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